UPMBiomedicals

GrowDex Customer Testimonials

“We tested using GrowDex as an alternative for animal derived extracellular matrices in cell based 3D high-throughput drug screening (HTS). The results demonstrated that GrowDex is compatible for use in large-scale 3D drug screens and supports long-term culture of primary patient derived tumor cell cultures.”

Juha K. Rantala, Ph.D., CEO, Principal Investigator at Misvik Biology

 

We compared the differentiation of the GrowDex epithelial cells in parallel to animal collagen-coated transfers, and found that the cells differentiated much faster and had much better three-dimensional epithelial growth – the oldest cells in the cultures are now over 500 days old!

Doris Wilflingseder, Assoc.-Prof., PhD, Institute for Hygiene and Medical Microbiology, Medical University of Innsbruck

 

” I noticed the GrowDex family of products during one of my visits of the vendor space of a conference. It turned out to be a wonderfully neutral ECM substrate, devoid of the vagaries of some of the growth-factor and ligand-rich products in common use. It made me realize how much of cellular behavior can be governed by ECM factors and that we should question even very commonly accepted cell culture protocols. With the ability to easily functionalize GrowDex, it could be a welcome alternative to probe the effects of ECM-bound proteins and their impact on cellular differentiation, locomotion, and survival. ”

Jan M. Bruder, PhD, Max Planck Institute for Molecular Biomedicine

“We have been using GrowDex-T in transplanting stem cells to the inner allowing them to extend to neurites. GrowDex-T works well in our application, as the material is easy to handle, injectable and we can adjust the stiffness of the matrix to match our cell type. Another great thing about GrowDex-T is that it is compatible with other nanobiomaterials, such as PODS-delivery systems.”

Akihiro J. Matsuoka, M.D., DMSc, Ph.D., FACS, Director, Audiology, Department of Otolaryngology-Head and Neck Surgery

 

“Animal models present certain limitations when studying impact of chemicals on the placenta. I believe that this is where GrowDex can play a really big role since preliminary data from our laboratory suggest that when human placental cells growing on 3D, they become hormonally active and recreate a much more relevant endocrine milieu to humans.”

Dr Emmanouil Karteris, Senior Lecturer and Head of the Cellular Endocrinology
Brunel University London, Uxbridge, United Kingdom

 

“In our hands, GrowDex showed excellent batch-to-batch consistency and was easy to handle, especially since no cross-linking is required. In my opinion, a clear strength of GrowDex is that it has lower tendency than other hydrogels to produce air bubbles, which would negatively influence cell viability and result in heterogeneity of the gel.”

Dr Darius Widera, Associate Professor in Stem Cell Biology and Regenerative Medicine, ERASMUS and Study Abroad Coordinator, University of Reading, School of Pharmacy

 

“GrowDex is a very potential 3D matrix because it is inert and fibre-like, and doesn’t exhibit mouse biology or contain mouse growth factors. This means that you can add human growth factors and build a human tissue-like infrastructure.”

Tuula Heinonen, Tampereen Yliopisto

“GrowDex is easy to use and reproducibly manufactured, giving batch-to-batch consistency. Imaging is simple and GrowDex can be shipped at ambient temperature without degrading. It's a really great product.”

Phil Stephens, Professor of Cell Biology, Cardiff University Biobank academic lead, College of Biomedical & Life Sciences