3D culture of neural cells is necessary to recapitulate the complex cell architecture of the central nervous system. As multicellular models develop, there is a need for well-defined matrix that supports the differentiation of iPSC-derived neural cells. Compared to traditional 2D culture, the differentiation of neural progenitor cells to neurons and glial cells in 3D environment represents a more physiological approach to model organ-level responses.
Robust neuronal organoid assays with GrowDex®
Animal free GrowDex hydrogels mimic the native soft tissue ECM providing the neural cells more in vivo -like 3D growth environment, creating in vitro platforms that can be used to investigate specific functions and conditions at both the single cells- and network-levels.