3D culture of neural cells is necessary to recapitulate the complex cell architecture of the central nervous system. As multicellular models develop, there is a need for well-defined matrix that supports the differentiation of iPSC-derived neural cells. Compared to traditional 2D culture, the differentiation of neural progenitor cells to neurons and glial cells in 3D environment represents a more physiological approach to model organ-level responses.
Robust neuronal organoid assays with GrowDex®
Animal free GrowDex hydrogels mimic the native soft tissue ECM providing the neural cells more in vivo -like 3D growth environment, creating in vitro platforms that can be used to investigate specific functions and conditions at both the single cells- and network-levels.
Related GrowDex-T application notes
Novel stem cell-based therapies for hearing loss: combination and application of Otic Neural Progenitor cells from hESC, PODs™, and GrowDex®-T
GrowDex-T brings superior imaging quality for phase contrast and brightfield imaging. This hydrogel is completely transparent making imaging and automated analysis easy.
With over 150 different assay protocols available GrowDex is our original hydrogel. Highly biocompatible GrowDex has been used widely for the culture of primary cells through to iPS and ES cells.