High throughput screening and high content screening in drug discovery
In drug development, HTS and HCS enable hit-to-lead identification and setting up dose-response curves, by utilizing automation robotics, image-based data analysis and liquid handling devices that together help quickly to screen large chemical compound libraries. These tests are typically conducted on 96-, 384- or 1536-well microplates.
HTS/HCS assays generate large data sets that help to identify the right compounds to modulate a particular biomolecular pathway. High-quality data sets provide the starting point for the target identification in the drug discovery process. That is why, it is important to choose the right high-quality cell-based assays for further assay development and biochemical compound testing.
GrowDex hydrogels' natural and animal-free features as well as the quality control manufacturing process supports reproducible assays without lot-to-lot variability. These make GrowDex hydrogels especially fitting for large-scale high throughput and high content screening assays in microtiter plates.
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